Bioinformatics Scientist - III (Senior)
12 months
San Diego, CA 92121
Qualifications:
Education: * Minimum qualification: Master's degree with 4+ years of experience in computational biology, bioinformatics or related fields. * Advance degree- PhD in computational biology, bioinformatics, or related fields. Required experience and skills: * Experience in biotech or pharmaceutical industries is a plus. * Advanced skills in a high-level programming language such as R or Python for data analysis and visualization. * Expertise in downstream analysis for common NGS data types, such as WGS/WES/panel-seq, bulk RNA-seq, single-cell RNAseq and spatial transcriptomics (experience in building NGS pipelines is not required but is a plus). * Basic understanding of disease biology and molecular/cellular mechanisms in immunology. * Expertise in network and systems biology is required. * Expertise in contemporary machine-learning/AI methods is a plus. Personality: * Problem-solving and collaboration skills, with rigorous and creative thinking. * Excellent communication, data interpretation presentation, and visualization skills. * Fluent in written and verbal English. * Adaptable and flexible. Are you a computational biologist with a passion for unraveling the complexities of the immune system? * If you have a strong foundation in bioinformatics, 'omics analysis, network biology, and systems biology, along with a deep understanding of molecular and cellular immunology, we'd love to hear from you. * Your work will be instrumental in driving precision medicine and drug development by dissecting the molecular mechanisms underlying immune-mediated diseases. * We welcome applications from individuals with a track record of innovative translational research in immunology, regardless of their current setting (clinical, academic, or industrial). Note: * 100% onsite role. * Remote working candidates will not be considered. * Positions available: 1
Responsibilities:
We are looking for a contractor with extensive experience in computational biology and join our immunology analytics team in Translational Genome Analytics, San Diego. * Use computational methods to identify molecular subtypes with unmet need in immune mediated diseases. * Conduct in-depth analyses to uncover the key biological functions and disease mechanisms driving disease subtypes. * Collaborate with multi-disciplinary teams to pinpoint potential therapeutic targets. * Contribute to accurately represent key disease states in model systems and other validation scenarios. * Work closely with discovery immunology teams in the iterative process of validation of therapeutic candidates and/or mechanistic hypotheses. * Summarize your findings and report conclusions to Merck stakeholders.
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