Research Associate, Vector Engineering

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

The Research Associate is a member of the Discovery group and will support the Vector Engineering Team in laboratory research activities towards development and testing of novel gene therapy products.

The Opportunity

• Performing routine assays across the different gene therapy research programs (e.g.molecular cloning, nucleic acid extraction, ELISA, qPCR, western blot, etc).

• Support development and Implementation of new assays (e.g. cell-based, enzymatic, immunoassays, NGS library preparation etc.) or optimization of existing assays as needed.

• Accurately document assay results and analyze data using an electronic lab notebook, technical documents and other reporting formats.

• Provide guidance to new and existing employees that will allow them to achieve autonomous operation in the lab ensuring work is completed according to project time lines.

Who You Are:

• Bachelor's degree required; Master's in a relevant field preferred.

• Minimum of 5-8 years laboratory experience. Experience with standard molecular biology techniques (PCR, plasmid purification, restriction digest, agarose gel electrophoresis) In-depth knowledge of a variety of cloning and recombineering techniques including ligation-dependent and homology-directed methods.

• Broad understanding of the technical and equipment needs in a lab as well as extensive hands-on experience with cell culture methods including cell line propagation, cell line cryopreservation, transfection.

Preferred Qualifications:

• Experience with AAV vector is a plus

• Working knowledge of protein detection assays including Western blotting and ELISA. Hands- on experience with either plate reader-based enzyme activity assays and/or ProteinSimple platform preferred.

• Experience in general and advanced lab techniques such as molecular cloning and plasmid design and construction, oligo design, qPCR, ELISA, cell culture, plate-based luciferase and/or enzymatic activity assays, SDS-PAGE/western blotting, etc.

• Familiarity of Electronic Lab Notebook (ELN) and Laboratory Information ManagementSystems (LIMS) a plus.

• Strong organizational skills.

• Excellent communication skills (both oral and written)

The expected salary range for this position based on the primary location of Philadelphia is $72,900 to $135,300.Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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