Technical Development Senior Scientist

Pharma Technical Development (PTD) focuses on developing robust manufacturing processes and quality control systems to efficiently transform scientific ideas into products. PTD reliably delivers quality products to patients enrolled in clinical studies around the world. PTD excels by creating an engaging and inclusive environment where everyone can bring their skills and talents to developing innovative medicines.

The Opportunity:

As a Technical Development Senior Scientist, you will be responsible for developing, optimizing, and performing analytical methods to characterize recombinant protein therapeutics or new therapeutic modalities. Utilizing techniques such as ultra-high performance liquid chromatography (UHPLC), mass spectrometry (MS), capillary electrophoresis (CE), and advanced spectroscopy methods (Raman, NIR, or NMR), you will drive the development, optimization, and qualification of analytical methods for characterization and GMP quality control of therapeutic proteins and new modalities.

In this role, you will provide analytical support to different functional groups within Pharma Technical Development and actively participate in cross-functional teams consisting of members from all areas of process development. You will author and review protocols, technical reports, scientific articles and contribute to regulatory submissions in support of clinical trials and licensure. Additionally you will:

• Develop and optimize chromatography-, capillary-, spectroscopy-, and mass spectrometry-based analytical methods to support protein characterization, process development, comparability assessment, method qualification/validation, and other late stage analytical activities.

• Perform physicochemical characterization of protein therapeutics (such as antibody drugs and new protein drug modalities) to determine critical quality attributes.

• Provide technical support of analytical method qualification, validation, and transfer activities.

• Author and review technical development documents and relevant sections of health authority filings.

• Hands-on, technical execution in the laboratory while providing mentorship to junior colleagues.

• Maintain timely and accurate lab records consistent with good documentation practices.

• Serve as a technical expert or representative and provide analytical knowledge and expertise to cross-functional teams.

Who You Are

• You possess a Ph.D. in Analytical Chemistry, Biochemistry, Chemical Engineering or related field with 0-2 years industry/post-doctoral experience.

• You have knowledge in the analytical characterization of proteins or related therapeutic modalities, and practical expertise in the application of innovative technologies LC-MS.

• You are self-motivated, have excellent organization, oral and written communication skills, and have demonstrated skills to work both independently and as a collaborative team member.

• You have demonstrated experience presenting data and insights for various audiences.

• You thrive in a dynamic, fast-paced environment and excel at managing various responsibilities while consistently meeting deadlines.

Preferred Experience:

• Working knowledge of sample preparation and data analysis automation

• Working knowledge of statistical methods, data analytics or multivariate analysis

• Familiarity or working knowledge of programming languages such as R, Python or Javascript

• Bioinformatics background in mass spectrometry, proteomics

Relocation benefits are approved for this posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $104,650 (min) - $149,500 (mid) - $194,350 (max). Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed in this link.

#LI-CA1

#ptcareers

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.