Principal Enterprise Architect

Job Title: Principal Enterprise Architect

Department: Technology. Office of CTO | Technology & Execution | Enterprise Architecture team

Reports To: Sr. Director, Enterprise Architecture

Job Summary: The Enterprise Architect will help shape and implement Myriad Genetics' next-generation technology stack, aligning architecture decisions with business growth, operational scale, and life sciences priorities. This role requires a pragmatic architecture leader who has successfully delivered modern enterprise platforms in healthcare, diagnostics, biotech, or life sciences environments.

This is a hands-on enterprise architecture role focused on translating business strategy into executable architecture across life sciences capabilities, including digital engagement, provider and patient experiences, data governance, integration, identity, automation, analytics, and AI-enabled workflows. The Enterprise Architect will partner with business, product, engineering, security, data, and operations teams to define target-state architecture, evaluate platform options, guide implementation, and prepare clear executive recommendations.

The ideal candidate has implemented modern platform capabilities such as integration platforms as a service (iPaaS), master data management (MDM), digital experience platforms (DXP), identity and access management (IAM), cloud, data platforms, intelligent document processing, and applied AI - not just evaluated them.

Responsibilities:

• Enterprise Architecture Strategy: Define architecture strategies, principles, standards, and roadmaps that connect Myriad's life sciences business priorities to scalable technology execution.
• Architecture Design & Governance: Design, review, and guide business, application, data, integration, security, and technology architectures across enterprise initiatives, ensuring alignment to platform strategy and long-term reuse.
• Technology Evaluation & Decision Support: Lead buy vs. build vs. hybrid evaluations for strategic capabilities, balancing business fit, technical fit, cost, risk, scalability, compliance, and speed to value.
• Next-Gen Platform Implementation: Provide architecture leadership for implementation of iPaaS, MDM, DXP, IAM, API management, cloud, data platforms, automation, intelligent document processing, and AI-enabled capabilities.
• Discovery & Stakeholder Alignment: Facilitate discovery, capability assessments, current-state/future-state mapping, and decision alignment across business, product, engineering, security, data, and operations teams.
• Executive Communication: Prepare concise recommendations, roadmaps, trade-off analyses, and decision summaries for senior leadership and governance forums.
• Business Case & Value Realization: Partner with business and finance teams on investment justification, total cost of ownership, ROI modeling, and measurable business outcomes.
• Delivery Partnership: Work closely with product, program, engineering, and vendor teams to keep implementation aligned to architecture intent, business outcomes, quality, timelines, and constraints.
• Modernization & Reuse: Identify opportunities to simplify, consolidate, modernize, and reuse technology capabilities across the enterprise.
• Risk, Security & Compliance: Identify technical, security, compliance, data, and operational risks and recommend practical mitigation strategies.
• Architecture Artifacts: Create practical artifacts such as capability maps, target-state diagrams, integration patterns, reference architectures, decision records, and roadmaps.
• Standards & Best Practices: Promote architecture standards, patterns, and practices that enable secure, consistent, and effective use of enterprise platforms.

Qualifications:

• Education: Bachelor's degree in Computer Science, Information Systems, or a related field; Master's degree preferred.
• Experience: Minimum of 10 years in IT architecture, including 5+ years in healthcare, diagnostics, biotech, or life sciences, with demonstrated experience implementing modern enterprise platforms.
• Skills: Strong architecture, analysis, communication, and stakeholder alignment skills; practical experience with enterprise architecture frameworks such as TOGAF; exposure to cloud, APIs, data platforms, Salesforce, Oracle, laboratory systems, portals, and SaaS ecosystems.
• Life Sciences Knowledge: Strong understanding of healthcare, diagnostics, biotech, or life sciences operating models, including regulatory, privacy, data, and interoperability considerations such as HIPAA, PHI, and FHIR.
• Technologies: Hands-on implementation exposure to iPaaS, MDM, DXP, IAM, API management, cloud, data platforms, intelligent document processing, AI-enabled workflows, and related integration and automation patterns.

Preferred Attributes:

• Delivery Leadership: Proven ability to guide complex, cross-functional technology initiatives from strategy through implementation.
• Innovation: Ability to apply emerging technologies pragmatically to improve business outcomes, user experience, and operational efficiency.
• Adaptability: Comfortable operating in a fast-changing environment with evolving priorities, platforms, and delivery models.
• Business Process Acumen: Understanding of procurement, legal, security, finance, and vendor management processes needed to move strategic technology decisions forward.
• Cross-Functional Partnership: Ability to align business, technology, security, finance, and vendor stakeholders around clear decisions and executable plans.

About the Team:

• You will be working with the Office of the CTO within Myriad Genetics' Enterprise Architecture team
• Our team partners across business and technology functions to shape enterprise strategy, guide major platform decisions, and deliver scalable digital transformation.
• We are focused on life sciences innovation, modern platform enablement, and architecture practices that improve provider, patient, commercial, operational, and data capabilities.

Required

• U.S. citizen or national
• Green Card holder
• Living full time in the USA

We take geographic location into account when determining base salary to ensure equitable and competitive compensation.

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