Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 99 |
Cambridge, Massachusetts
Overview: Alnylam is seeking a progressive, dynamic, business-focused HR Business Partner to support several Commercial leaders and their teams. Reporting to the VP HR, Commercial, this HR Business Partner will play a key role in delivering...
4h
| Job Type | Full Time |
Senior Director, IT Finance Leader
Cambridge, Massachusetts
Overview: We are seeking a strategic, results-driven IT leader to own the technology vision and execution for Finance. This leader will serve as a crucial bridge between technical capabilities and strategic business needs, partnering direct...
4h
| Job Type | Full Time |
Principal Associate Scientist, Biology
Cambridge, Massachusetts
Overview We are seeking a highly motivated and skilled Principal Associate Scientist to join our innovative Research & Development (ReDev) team focused on advancing next-generation oligonucleotide-based therapeutics. The ideal candidate wil...
15h
| Job Type | Full Time |
Cambridge, Massachusetts
The Director is accountable for the operational execution of the Clinical Development Plan (CDP). As a disease area thought partner, the Director is responsible for the development of the program-level operational strategy and ensuring cros...
21h
| Job Type | Full Time |
Associate Director, Early Development Quality
Cambridge, Massachusetts
Overview The Associate Director, Early Development Quality provides strategic, upstream quality leadership across nonclinical development programs, with a focus on de-risking study design, biomarker strategies, and external laboratory partn...
1d
| Job Type | Full Time |
Legal Director, Global Medical Affairs & Pipeline
Cambridge, Massachusetts
The Legal Director, Global Medical Affairs & Pipelinewill provide expert advice and strategic and tactical counseling to Global Medical Affairs teams to support compliance with applicable laws and regulations. This position will report to t...
2d
| Job Type | Full Time |
Associate Director, Site and Monitoring Health
Cambridge, Massachusetts
Overview The Associate Director, Site and Monitoring Health will provide strong leadership, GCP expertise and clinical operations experience to drive the monitoring strategy for trials in their assigned program(s). They are responsible for ...
3d
| Job Type | Full Time |
Manager, Patient Services Operations
Cambridge, Massachusetts
Overview The Manager, US Patient Services Operations role is a critical component of the Patient Services Operations team. Reporting to the Associate Director, US Patient Services Operations, within the Technology Enablement pillar, this ro...
3d
| Job Type | Full Time |
Regional Business Director - TTR (South/Central Florida - Miami, Ft. Lauderdale, Tampa)
Cambridge, Massachusetts
Overview We are looking for an experienced Regional Business Director (RBDs to support the promotion of AMVUTTRA (vutrisiran). The U.S. Food and Drug Administration (FDA) recently approved the supplemental New Drug Application (sNDA) for AM...
3d
| Job Type | Full Time |
Manager, Manufacturing Systems
Cambridge, Massachusetts
Overview The Manager, Manufacturing Systems is an integral part of the Internal Manufacturing team. This role is the end-user subject matter expert for the Manufacturing Execution System (MES) and Real-Time Modeling System (RTMS), The SME w...
5d
| Job Type | Full Time |